sample postdoc research statement

Search committee members are extraordinarily busy , so you must structure your statement strategically

Abstract : 10-15 lines at most. In a nutshell, what you work on and your plans for the next ten years in terms of the impact you hope to make on your field.

Ph.D work/background . What you worked on and what your work showed, demonstrated, elucidated, etc. Be very direct and to the point. Throw in anything the reader (who won’t be a specialist) will need to understand what you do.

Current postdoctoral research . Again, what you work on and what you hope to achieve. If needed, use a numbered list or bullet points.

Future Directions . I) What you hope to achieve over the next ten years; II) What you hope to achieve over the next 4-7 years; III) What you’ll tackle from the get-go(low-hanging fruits). Obviously, these are not sequential, but parallel. This section should be about 50-60% of the overall 3-5 page statement.  Once you're done, share your research statement with your faculty advisor and other colleagues for critical feedback.

Research Statements

The research statement is a critical document in academic and research applications, such as postdoctoral fellowships or faculty positions. It is a concise summary of your research background, current research activities, and future research goals. It serves as a tool to showcase the independent research you conduct, highlight your research agenda and goals, demonstrate your writing ability, and articulate potential funding opportunities you plan to pursue.

Printable Research Statement Guide

Length and Format

• 1-2 single-spaced pages (unless specified otherwise) • Adheres to the specific length and content requirements of each application

Audience and Context

• Write your research statement for an audience of professionals in your field. • Assume that the readers have a solid foundation in the subject matter.

Introduction

Begin with an introduction that contextualizes your work within your broader field. Discuss the larger questions your research addresses and the significance of those questions within the field.

Research Interests

Describe your specific research interests within the broader context. What questions or problems are you focused on, and why are they important?

Mention any academic publications, conference presentations, or collaborations resulting from your past research.

Incorporating your Research

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Past Research

Provide a concise history of your past research. Discuss the initial questions you aimed to answer, the findings you obtained, and how your work contributed to the field.

Present Research

Discuss your ongoing research. What questions are you currently investigating, and what have you discovered so far? Explain how your current work connects to the broader academic discourse, and mention any forthcoming publications, conferences, or other professional activities. Include specific examples of your successes.

Future Research

Detail plans for future research. What questions do you intend to address next, and how do you plan to answer them? Explain how the institution and program to which you are applying can support your research goals. Discuss the potential implications of your future work.

Tie It All Together

Ensure your statement is logically connected, showing a progression in your research journey. Highlight the primary question or theme that has guided your academic career, its importance to the field, and how each stage of your work has contributed to addressing that question.

Your research statement should convey your motivation and passion for your work. Ultimately, a well-crafted research statement should demonstrate your expertise, potential contributions to the field, and compatibility with the academic institution to which you are applying. It should provide a clear and compelling narrative of your research journey and ambitions.

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Research Statement

Research statements are a frequent component of the academic job market application portfolio and one of the more field-specific documents. In a research statement, you are explaining to the search committee your scholarly profile, research agenda, impact of your work, and how your scholarship fits into the department and institution.

While the research statement can vary widely depending on field and institution, in general, research statements:

• Are up to two pages in length
• Written as first-person narratives (e.g., "My research focuses on ..."; "I consider ...")
• Address research topic and details
• Demonstrate methodologies used, approach, techniques, etc.
• Address the impact of your work
• Speak to future research agendas
• Can address questions of diversity, equity, and inclusion

Content Considerations

While your research statement needs to specify your current research and the foundation you have developed in your doctoral program, you also need to speak to how this current work relates to a future-looking research agenda. You want to talk the search committee through the evolution of your research from current project to future pathways. Think of the statement in three parts:

• What is the current state of research and why is it important to your field?
• What immediate work (publications, grants, impact) will you get out of this research? Why is it important?
• How will you use the skills built in the first two parts to develop future projects? In what direction do you hope to grow? How is this research possible at this particular institution?

Finally, think about the reader of your research statement: a search committee that may be familiar with your field but still requires an easily legible and accessible statement. While drafting and revising, keep this reader in mind:

• Will they understand the jargon?
• Can your research be understood by colleagues outside of your adviser, committee, and immediate peers?
• What about the student population at this institution? How can they be involved and help develop your research agenda?
• What resources (equipment, access, buildings) does the institution have and how can that help with your research agenda?

You as a Peer

Of utmost importance in a research statement is that you are not talking as a graduate student. You are not proposing a dissertation or potential experiment. In the research statement, you are delineating the contours of your research so a hiring committee can determine if it is in the interest of the department to invest in your candidature. Think about the position you are applying to:

• How does your research style fit within the department?
• How does your research complement projects or programs already underway within the department?
• How would your research engage with the department’s broader interests (e.g., their teaching output or interdisciplinary perspectives)?
• How would your research benefit the institution (grants, collaborations, new courses, new projects, etc.)?

As with all application documents, make sure to have multiple eyes on the content before submitting your statement. Take advantage of the support Northwestern provides from the Graduate Writing Place, Office of Fellowships, and Northwestern Career Advancement .

Postdocs can make appointments for individualized feedback with the Office of Postdoctoral Affairs .

Humans To Robots Laboratory

Empowering every person with a collaborative robot, writing a research statement for graduate school and fellowships.

Writing a research statement happens many times throughout a research career. Often for the first time it happens when applying to Ph.D. programs or applying to fellowships. Later, you will be writing postdoc and faculty applications. These documents are challenging to write because they seek to capture your entire research career in one document that may be read in 90 seconds or less.

Think of the research statement as a proposal. Whether you are applying for a Ph.D. program or for a faculty position, you are trying to convince the reader to invest in you. To decide whether to make this investment they need to know three things: 1) what will you do with the investment, 2) why is that an important problem ? and 3) what evidence is there that you will be successful in achieving the goals that you have set out.

The first paragraph, therefore, should describe what problem you are aiming to solve, and why it is an important problem. One common failure mode is to be too general and vague in this paragraph. Yes we all want to solve AI! But you want to write about your specific take, angle, or approach. This will set up the rest of the statement, about why you are the one person uniquely qualified to solve the problem you set up here. Sometimes people shy away from being too specific, because they worry that it will put them in a box. Don’t worry! Research interests always evolve, and you will not be signing in blood to do this exact research plan. It is better to ere on the side of being too specific because it shows you can scope out an exciting project and that you have good ideas, even if you are not sure that this specific idea is the one you will eventually pursue.

The next paragraphs should describe your past work as it fits into the research vision you have outlined in the first paragraph. You can start with a paragraph for each project or paper you have worked on. The paragraphs can be more or less the abstract for the paper . However you should be clear exactly what your role in the project was, give credit to collaborators, and spend more time on the parts of the project you contributed to directly. You also need to tie it to the research vision in paragraph 1. The strongest statement presents your life, as an arrow that points unambiguously towards solving the research question you have outlined in paragraph 1. Of course, no one’s life is actually an unambiguous arrow! However I think it helps to think that way because you are trying to tie the projects together to show how they have prepared you and furthered you along the research trajectory. Even if this project wasn’t directly connected in terms of its research questions, you can write about how it taught you technical tools that you can apply to your research objective, or how it taught you something that led to your current research objective.

The last paragraphs should describe concretely what you plan to do next. If you are applying to a Ph.D. program, you should name the groups you wish to work with and explain why they are a good fit for you. For a fellowship, you should describe why this work is a good fit for the work done by the organization you are applying to.

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Research Statements

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A research statement is used when applying for some academic faculty positions and research-intensive positions. A research statement is usually a single-spaced 1-2 page document that describes your research trajectory as a scholar, highlighting growth: from where you began to where you envision going in the next few years. Ultimately, research productivity, focus and future are the most highly scrutinized in academic faculty appointments, particularly at research-intensive universities. Tailor your research statement to the institution to which you are applying – if a university has a strong research focus, emphasize publications; if a university values teaching and research equally, consider ending with a paragraph about how your research complements your teaching and vice versa. Structures of these documents also varies by discipline. See two common structures below.

Structure One:

Introduction: The first paragraph should introduce your research interests in the context of your field, tying the research you have done so far to a distinct trajectory that will take you well into the future.

Summary Of Dissertation: This paragraph should summarize your doctoral research project. Try not to have too much language repetition across documents, such as your abstract or cover letter.

Contribution To Field And Publications: Describe the significance of your projects for your field. Detail any publications initiated from your independent doctoral or postdoctoral research. Additionally, include plans for future publications based on your thesis. Be specific about journals to which you should submit or university presses that might be interested in the book you could develop from your dissertation (if your field expects that). If you are writing a two-page research statement, this section would likely be more than one paragraph and cover your future publication plans in greater detail.

Second Project: If you are submitting a cover letter along with your research statement, then the committee may already have a paragraph describing your second project. In that case, use this space to discuss your second project in greater depth and the publication plans you envision for this project. Make sure you transition from your dissertation to your second large project smoothly – you want to give a sense of your cohesion as a scholar, but also to demonstrate your capacity to conceptualize innovative research that goes well beyond your dissertation project.

Wider Impact Of Research Agenda: Describe the broader significance of your work. What ties your research projects together? What impact do you want to make on your field? If you’re applying for a teaching-oriented institution, how would you connect your research with your teaching?

Structure Two:

25% Previous Research Experience: Describe your early work and how it solidified your interest in your field. How did these formative experiences influence your research interests and approach to research? Explain how this earlier work led to your current project(s).

25% Current Projects: Describe your dissertation/thesis project – this paragraph could be modeled on the first paragraph of your dissertation abstract since it covers all your bases: context, methodology, findings, significance. You could also mention grants/fellowships that funded the project, publications derived from this research, and publications that are currently being developed.

50% Future Work: Transition to how your current work informs your future research. Describe your next major project or projects and a realistic plan for accomplishing this work. What publications do you expect to come out of this research? The last part of the research statement should be customized to demonstrate the fit of your research agenda with the institution.

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Research statements for faculty job applications

The purpose of a research statement.

The main goal of a research statement is to walk the search committee through the evolution of your research, to highlight your research accomplishments, and to show where your research will be taking you next. To a certain extent, the next steps that you identify within your statement will also need to touch on how your research could benefit the institution to which you are applying. This might be in terms of grant money, faculty collaborations, involving students in your research, or developing new courses. Your CV will usually show a search committee where you have done your research, who your mentors have been, the titles of your various research projects, a list of your papers, and it may provide a very brief summary of what some of this research involves. However, there can be certain points of interest that a CV may not always address in enough detail.

• What got you interested in this research?
• What was the burning question that you set out to answer?
• What challenges did you encounter along the way, and how did you overcome these challenges?
• How can your research be applied?
• Why is your research important within your field?
• What direction will your research take you in next, and what new questions do you have?

While you may not have a good sense of where your research will ultimately lead you, you should have a sense of some of the possible destinations along the way. You want to be able to show a search committee that your research is moving forward and that you are moving forward along with it in terms of developing new skills and knowledge. Ultimately, your research statement should complement your cover letter, CV, and teaching philosophy to illustrate what makes you an ideal candidate for the job. The more clearly you can articulate the path your research has taken, and where it will take you in the future, the more convincing and interesting it will be to read.

Separate research statements are usually requested from researchers in engineering, social, physical, and life sciences, but can also be requested for researchers in the humanities. In many cases, however, the same information that is covered in the research statement is often integrated into the cover letter for many disciplines within the humanities and no separate research statement is requested within the job advertisement. Seek advice from current faculty and new hires about the conventions of your discipline if you are in doubt.

Timeline: Getting Started with your Research Statement

You can think of a research statement as having three distinct parts. The first part will focus on your past research, and can include the reasons you started your research, an explanation as to why the questions you originally asked are important in your field, and a summary some of the work you did to answer some of these early questions.

The middle part of the research statement focuses on your current research. How is this research different from previous work you have done, and what brought you to where you are today? You should still explain the questions you are trying to ask, and it is very important that you focus on some of the findings that you have (and cite some of the publications associated with these findings). In other words, do not talk about your research in abstract terms, make sure that you explain your actual results and findings (even if these may not be entirely complete when you are applying for faculty positions), and mention why these results are significant.

The final part of your research statement should build on the first two parts. Yes, you have asked good questions, and used good methods to find some answers, but how will you now use this foundation to take you into your future? Since you are hoping that your future will be at one of the institutions to which you are applying, you should provide some convincing reasons why your future research will be possible at each institution, and why it will be beneficial to that institution, or to the students at that institution.

While you are focusing on the past, present, and future or your research, and tailoring it to each institution, you should also think about the length of your statement and how detailed or specific you make the descriptions of your research. Think about who will be reading it. Will they all understand the jargon you are using? Are they experts in the subject, or experts in a range of related subjects? Can you go into very specific detail, or do you need to talk about your research in broader terms that make sense to people outside of your research field focusing on the common ground that might exist? Additionally, you should make sure that your future research plans differ from those of your PI or advisor, as you need to be seen as an independent researcher. Identify 4-5 specific aims that can be divided into short-term and long-term goals. You can give some idea of a 5-year research plan that includes the studies you want to perform, but also mention your long-term plans, so that the search committee knows that this is not a finite project.

Another important consideration when writing about your research is realizing that you do not perform research in a vacuum. When doing your research you may have worked within a team environment at some point, or sought out specific collaborations. You may have faced some serious challenges that required some creative problem-solving to overcome. While these aspects are not necessarily as important as your results and your papers or patents, they can help paint a picture of you as a well-rounded researcher who is likely to be successful in the future even if new problems arise, for example.

Follow these general steps to begin developing an effective research statement:

Step 1: Think about how and why you got started with your research. What motivated you to spend so much time on answering the questions you developed? If you can illustrate some of the enthusiasm you have for your subject, the search committee will likely assume that students and other faculty members will see this in you as well. People like to work with passionate and enthusiastic colleagues. Remember to focus on what you found, what questions you answered, and why your findings are significant. The research you completed in the past will have brought you to where you are today; also be sure to show how your research past and research present are connected. Explore some of the techniques and approaches you have successfully used in your research, and describe some of the challenges you overcame. What makes people interested in what you do, and how have you used your research as a tool for teaching or mentoring students? Integrating students into your research may be an important part of your future research at your target institutions. Conclude describing your current research by focusing on your findings, their importance, and what new questions they generate.

Step 2: Think about how you can tailor your research statement for each application. Familiarize yourself with the faculty at each institution, and explore the research that they have been performing. You should think about your future research in terms of the students at the institution. What opportunities can you imagine that would allow students to get involved in what you do to serve as a tool for teaching and training them, and to get them excited about your subject? Do not talk about your desire to work with graduate students if the institution only has undergraduates! You will also need to think about what equipment or resources that you might need to do your future research. Again, mention any resources that specific institutions have that you would be interested in utilizing (e.g., print materials, super electron microscopes, archived artwork). You can also mention what you hope to do with your current and future research in terms of publication (whether in journals or as a book), try to be as specific and honest as possible. Finally, be prepared to talk about how your future research can help bring in grants and other sources of funding, especially if you have a good track record of receiving awards and fellowships. Mention some grants that you know have been awarded to similar research, and state your intention to seek this type of funding.

Step 3: Ask faculty in your department if they are willing to share their own research statements with you. To a certain extent, there will be some subject-specific differences in what is expected from a research statement, and so it is always a good idea to see how others in your field have done it. You should try to draft your own research statement first before you review any statements shared with you. Your goal is to create a unique research statement that clearly highlights your abilities as a researcher.

Step 4: The research statement is typically a few (2-3) pages in length, depending on the number of images, illustrations, or graphs included.  Once you have completed the steps above, schedule an appointment with a career advisor to get feedback on your draft. You should also try to get faculty in your department to review your document if they are willing to do so.

Explore other application documents:

How to write a research statement for a postdoc fellowship

In this post, I share the research statement I wrote to become a finalist in a prestigious postdoctoral fellowship competition called the Owen Chamberlain Postdoctoral Fellowship at Berkeley Lab.

At the time of the application, I did not have any main-author papers published yet but some in the pipeline.

If you are wondering what do you even write in a research statement, I am totally with you.

I felt the same way.

What do I say?

Then I learned that what you mainly say in a research statement is what you have done already and how that makes you great.

I don’t know exactly how many people apply for postdoc fellowships like these but I have heard it’s hundreds.

I was selected as a finalist along with 4 or 5 others.

I had loads of fun visiting the place, interviewing, and giving talks.

At the interview, they told me they didn’t yet know their budget that year.

They ended up not giving the fellowship to anyone that year – as far as I know.

I loved the experience though and here’s the research statement!

Research statement

Multimessenger astronomy and astrophysics, although broad, capture my research interests most accurately. Be it neutrinos, X-rays, dark matter, or gravitational waves, I find these rapidly-growing avenues of studying the Universe most promising, and the Chamberlain Fellowship would allow me to expand on my current expertise while applying the knowledge, skills, and experience gained during my Ph.D.

My Ph.D. is focused on a NASA long-duration balloon experiment for ultra-high-energy (> 10 18 eV) neutrino detection called the ANtarctic Impulsive Transient Antenna (ANITA). ANITA uses the polar vortex to orbit in roughly circular trajectories, at an altitude of ~ 40 km, over the continent of Antarctica, for about a month during the Austral Summer. This experiment provides a unique opportunity to study high energy astrophysical phenomena by means of an emerging cosmic messenger, namely the neutrino. There have been four ANITA missions so far.

ANITA searches for radio pulses in the 200 – 1200 MHz frequency range, produced by neutrino interactions in the Antarctic ice. The human activity that produces radio waves in the same frequency range, such as military communications satellites, has been known to interfere with and even prevent ANITA science operations. To mitigate radio interference, I built tunable filters for the ANITA-IV mission (2016). During my deployment in Antarctica last year, after a successful launch of ANITA-IV, I operated the tunable filters in real-time. The filters helped to increase the instrument livetime of ANITA by almost a factor of 3. Details are in our pre-print at https://arxiv.org/abs/1709.04536 .

At present, I am studying and classifying anthropogenic noise using data from the ANITA-II and ANITA-III flights. I am a lead contributor to the development of a new analysis technique to search for a diffuse flux of ultra-high-energy neutrinos. Additionally, I am leading the development of new techniques to perform the first search for afterglow neutrinos from Gamma Ray Bursts using data from the ANITA-III and ANITA-IV flights. We are expecting to publish results from these analyses at the end of the Fall of 2017 and in the Spring of 2018, respectively.

I am interested in experiments such as Daya Bay and DUNE, that probe the Universe with neutrinos at energies complementary to those probed by ANITA. These experiments will allow me to increase my breadth both in their particle physics and astrophysics goals. Additionally, I am interested in the next-generation dark matter experiment LZ, that aims to answer fundamental questions about the Universe through the detection of dark matter.

Due to my experience with building and deploying ANITA-IV, I am well-placed to make strong contributions to detector development, testing, calibration, and deployment for new and upcoming experiments. By the time I graduate, I will have worked on multiple analyses using complementary techniques involving data from three flights of ANITA, making me well-rounded and capable of leading analysis projects for the above-mentioned experiments. In conclusion, my research interests align with multiple opportunities that could be supported by the Chamberlain Fellowship, and that would also benefit from my background in particle astrophysics instrumentation and analysis work.

Here is a related post where I talk about the dangers of taking too long to finish a Ph.D. and its impact on winning postdoctoral fellowships.

Dangers of a Ph.D. Taking Too Long

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10 responses to “how to write a research statement for a postdoc fellowship”.

In my experience, communication is extremely important especially when you use a virtual assistant. Failure in this area can lead to a lot of business delays. Finding the right resources to improve communication is very valuable, and will help you & your virtual assistant with knowledge to avoid problems.

This is a very helpful post, thank you! I like that your research statement is not very long and can be easily reverse engineered to get a general outline for any discipline. You’re a great writer 🙂

Like!! Thank you for publishing this awesome article.

Your post is very helpful!! Thank you!

Awesome, thanks!

Thank you very much my dear for this extraordinary help

Thank you very much for this very useful guide

Thank you, this is very helpful!!!

I love how you explained your research in a way such that even someone like me, who is studying immunology, can understand!!

Yayyy!!! Good luck!

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The Professor Is In

Guidance for all things PhD: Graduate School, Job Market and Careers

Dr. Karen’s Rules of the Research Statement

By Karen Kelsky | September 16, 2016

We’ve looked at the Cover Letter and the CV  and the Teaching Statement .  Today we look at the Research Statement.

An expanded and updated version of this post can now be found in chapter  27 of my book, the professor is in: the essential guide to turning your ph.d. into a job ..

Today, at long last, and in response to popular demand, a post on the Research Statement.

I have, perhaps, procrastinated on blogging about the Research Statement because at some level I felt that the rules might be more variable on this document, particularly with regard to length.

But in truth, they really aren’t.

The RS should be be two pages long for any junior candidate in the humanities or soft social sciences.  Two pages allows for an elaboration of the research well beyond the summary in the cover letter that gives the search committee substantial information to work with. Those junior candidates in the hard sciences and fields like Psychology can have 3-4 page research statements.

I strongly urge all job-seekers to investigate the norms of their individual fields carefully, and follow the advice they receive on this matter from experts in their own fields.  Just never simply ASSUME that longer is better in an RS or in any job document.

By the way, the RS to which I refer here is the document sometimes requested as part of a basic job application.  This is NOT the “research proposal” required by specific fellowship or postdoc applications!   Those will specify a length, and should be written to follow the outline I describe in Dr. Karen’s Foolproof Grant Template .) They are a totally different genre of document; don’t confuse the two!

Anyway, back to the RS: there are undoubtedly a number of excellent reasons that people could give for writing a longer RS, based on thoroughness or detail or concerns for accuracy. And I would acknowledge those principles as valid ones.

But they would all come second to the single most important principle of all job market writing, in my view, which is the principle of search committee exhaustion.

Search committee members are exhausted, and they are overwhelmed and distracted. There simply is no bandwidth in their brains or their psyches to handle the amount of material they are required to read, when searches routinely garner between 300 and 1000 applications.

Anything that feels “long” is going to be resented just by virtue of its length. And resentment is categorically what you don’t want a search committee member feeling about your job application materials.

So, in short, the Research Statement, just like the Teaching Statement , needs to be one to two pages in length, single spaced.  And like the TS, it needs to be in 11 or 12 point font, and have decent one-inch margins.

What are the other rules? Here they are:

• Print the RS on regular printer paper. Do not use letterhead for this or the TS, and do not use any special high grade paper.
• Put your name and the words “Research Statement” centered at the top.
• If unsure how to structure, use a 5-paragraph model as follows:

[… edited… ] 

Here are some additional principles:

• A RS (like a TS) is not tailored to a school overtly. While you may subtly adjust your project descriptions to speak to a specific type of job, you do not refer to any job or department or application in the statement itself.
• Do not refer to any other job documents in the RS (ie, “As you can see from my CV, I have published extensively….”)
• As in all job documents, remain strictly at the level of the evidentiary. State what you did, what you concluded, what you published, and why it matters for your discipline, period. Do not editorialize or make grandiose claims (“this research is of critical importance to…”).
• Do not waste precious document real estate on what other scholars have NOT done. Never go negative. Stay entirely in the realm of what you did, not what others didn’t.
• Do not position yourself as “extending” or “adding to” or “building off of” or … [what follows is edited…]
• Do not refer to other faculty or scholars in the document. The work is your own. If you co-authored a piece…
• Do not refer to yourself as studying “under” anybody…
• Do not forget to articulate the core argument of your research. I am astounded at how often (probably in about 80% of client documents) I have to remind clients to …
• Give a sense of a publishing trajectory, moving from past to present…
• Make sure you are not coming across as a one-trick pony. The second major project must be clearly distinct …
• Use the active voice as much as possible, but beware a continual reliance on “I-Statements”, as I describe in this post, The Golden Rule of the Research Statement.

I will stop here. Readers, please feel free to add more in the comments.  I will add to this post as further refinements come to mind.

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Reader Interactions

August 30, 2012 at 12:38 pm

I am interested in applying for Ph.D programs in the UK and they ask for a Research Proposal…is this the same thing as a Research Statement?

August 30, 2012 at 12:59 pm

No, they are looking for what you might think of as a research protocol, so literally your background, literature review, hypotheses and methods. You would need to convey how this is a unique area of research that is novel and adds to the existing literature; they are assessing the novelty of your research and how you would conduct the study. PhD programs in the UK are heavily researched based; you would need to show that you could literally hit the ground running to do your PhD. A major difference is that UK PhD’s usually take 3-4 years full-time and this is stringently enforced. I have a PhD from the UK and there are obviously pros and cons compared to the US system but you need to be a confident researcher if you’re planning to take that route.

August 30, 2012 at 1:28 pm

No: a Research Proposal is intended as a pitch for a specific project, or the research programme you will undertake within a specific timeframe (such as a PhD or a post-doc). A Research Statement is used for applications for jobs and occasionally fellowships, and outlines the research you have *already* completed, and what you plan to pursue next. So your Research Statement will describe your doctoral thesis as a finished (or very nearly finished) product, and list the publications generated by your doctoral work and any subsequent projects.

August 30, 2012 at 2:12 pm

No, a research proposal is a description of what you would like to do for you PhD research. Essentially an outline of your expected PhD thesis (which can of course change later once you’ve been accepted and started working on your research) with a short lit review, an identification of a research gap that you plan to address and a brief outline of proposed methods.

August 30, 2012 at 12:46 pm

What about in the case where you are asked to provide a “Teaching and Research Statement” in addition to a statement of your teaching philosophy? I have gone for a one page statement which focuses on my research but links that to my teaching so as not to repeat too much from my philosophy or my cover letter. Any thoughts from others?

August 30, 2012 at 5:02 pm

I’m preparing a “Teaching and Research Statement” and have kept it at 2 pages (1 page for teaching and 1 for research). Do others think that’s OK? If it’s 1 page total, for both teaching and research, then how much could I really say? That’s so short, less room than a 2-page cover letter.

September 1, 2012 at 9:05 am

Yes, on occasions where jobs ask for that combined statement, I always work with clients to do a two page document, with one page devoted to each part.

September 20, 2017 at 10:09 am

Found the blog this week… I wish I found sooner!! Gongrats! One add-on question: in the case of a combined document, would you start with the RS and then TS, or it doesn’t make much difference?

September 21, 2017 at 9:56 am

I’d start with RS in general, but it would depend on the job – teaching-centric jobs would be the reverse.

September 16, 2021 at 7:13 pm

Hello, so glad I found your blog! The application I am putting together requests a statement of research philosophy, a teaching philosophy, and a combined research and teaching interests statement. In this case, would one page combined be sufficient with a much briefer review of interests in each area (given that so much more detail is available in the philosophy statements)?

August 30, 2012 at 1:21 pm

In my field in R1 jobs it is pretty rare that one is asked to prepare a research statement. This stuff does in the cover letter. Any insight into when one is asked for this?

August 30, 2012 at 1:27 pm

Field dependent, but as KK points out, you should have a research paragraph (or two) in your cover letter anyway…

August 30, 2012 at 1:26 pm

The above echoes my experience. One obvious caveat would be postdocs and such that either stipulate a longer statement length (the ol’ two page Fulbright IIE style), or suggest a wider range of material should be included.

August 30, 2012 at 2:50 pm

Thanks for the tips – a very useful post! How do these apply to postdoc applications?

– If the required length of the research statement is not stipulated, would one page also be sufficient for a postdoc application?

– Also, what is the convention for naming (with title) your advisor in the cover letter – should this also be avoided?

August 30, 2012 at 1:30 pm

In terms of the 5-paragraph model, where would you include subsequent projects, i.e if you are on your second or third post-doc. Do you give equal time/space to each project you have completed, or just the basic run-down and focus more on current or upcoming work?

August 30, 2012 at 3:46 pm

This is a good question. If you’re well beyond the diss, then you will use the “diss” para to describe your most important recent research, then at the end of that para or in the next one, indicate with a sentence or two the research that preceded it (demonstrating an organic connection between them if possible), with a major publication or two. And then from that, move to the next major project. So it’s a bit more of a zig zag, with the past sandwiched between (and subordinate to) the present and the future.

August 30, 2012 at 3:47 pm

Let me respond in a different way. if you are a senior scholar applying for an associate or full position, then your RS may certainly be longer than one page (although I’d cap it at two, myself). The one page rule applies most to those who are seeking their first or second assistant professor position.

August 30, 2012 at 4:10 pm

Where is the appropriate place to highlight (solo or lead-author) publications developed outside of your dissertation work? For example, a secondary area of inquiry that runs tangential to your core area of research.

September 1, 2012 at 9:08 am

That can get another paragraph. Now, this is tricky. If you have an *extensive* secondary body of work for whatever reason then in that case, you may be one of the people who can go onto two pages. This is rare—most job seekers just have their diss, its pubs, and a planned second project, and that can all go on one page. If you have a small body of secondary research, that can also still fit on one page. So the judgment call comes in knowing how much is “too much” to legitimately fit on one page. Questions like that are what people hire me for!

August 30, 2012 at 5:07 pm

I’m wondering about repeating myself. The 5-paragraph format for the research statement is very similar to the format for the cover letter. So should we more briefly discuss points we’ve fleshed out in the cover letter, to save the space for points that are not in the cover letter? Or is repeating the info in the research statement and cover letter OK/expected? (If you’re repeating yourself, then there’s the issue of figuring out X different ways to say the same thing.)

I answer this in another response, but basically you have the space here to go into far more detail about the scholarship itself—the methods, the theoretical orientation, a very brief and edited literature context, and a strong statement of contribution to the discipline. You can give chapter summaries of about one sentence each, and you can also describe the publications in a sentence or two (not possible in the job letter). And the biggest thing in the RS is the description of the second project. The cover letter devotes a very short paragraph to that, of approximately 2-3 sentences, but in the RS, it can get a full-sized paragraph.

January 21, 2020 at 1:11 pm

This is a very delayed response, but I’m hoping you still get the notification! I want to make sure that it’s appropriate to cite specific authors in describing the lit context. Thank you much!

August 30, 2012 at 7:30 pm

I struggle with para. 4 because I have 3 major post-diss projects in mind. 2 are off-shoots of the diss. material in the sense that they contribute to the same field as my diss. but look at very different aspects than my diss. covered. The 3rd project is a completely different trajectory with little-no connection to my diss. I fear it sounds “out of left field” as they say, but it’s my dream-project. So I’m not sure how to communicate all of these interests. Thoughts?

September 1, 2012 at 9:12 am

This is a huge question, and one that I’m going to edit the post to include. It is critical that no job seeker propose more than one next project. This may seem counter-intuitive. Surely, the more ideas I have, the more intellectually dynamic I look, right? Wrong. Anything above one major post-diss project makes you look scattered and at risk in your eventual tenure case. A tenure case requires a clear and linear trajectory from the diss, its pubs, to a second project, and its pubs.

Now, I hasten to add that this rule applies most firmly in the humanities and humanistically inclined social sciences. In the hard sciences, and experimental or lab-based social sciences, the rhythm of research and publishing is different and different rules might possibly apply, with a larger number of smaller-scale projects possible. But in book fields, you need to do one book…and then a second book…for tenure.

September 4, 2012 at 9:49 am

thanks Karen, I will keep this in mind

October 22, 2016 at 9:01 am

Do you know of a source for more information about this problem from the hard sciences and engineering perspective?

August 30, 2012 at 10:02 pm

In a research proposal (i.e., for a specific postdoc), what is the appropriate length of time for revising a dissertation for publication? My instinct is, for a 3-year program, to devote 2 years to revision/publication, and one year to the new research project. Is this too slow, too fast, too hot, too cold, or just right?

September 1, 2012 at 9:00 am

To my mind that is exactly right. However, I know of a major Ivy League 3-year fellowship that expects 3 years to be spent on the first book. I find that baffling. As a postdoc you have few teaching obligations and almost no committee/service work….why would it require three years to transform your diss to a book in that environment? This particular app does allow you to *optionally* propose a second project for the third year, and I recommend that all applicants do that.

August 30, 2012 at 10:07 pm

Karen, thanks for this and all of your other helpful posts. I’m a sociology phd student at a top department, and served on the hiring committee last year. Not a single applicant made it onto our short list (or even the “semifinalist” list of 30 candidates) with less than a 2 page research statement (and most were 2.5-3 pages). Maybe my institution is unique, or maybe they were poorly written and not as detailed as they could have been in one page. But I just wanted to share my experience for any sociologists reading this blog.

September 1, 2012 at 9:01 am

That’s interesting. That would seem to be fetishizing length qua length…. the work can be described in one page when the one page is well written.

September 4, 2012 at 7:45 am

I’m in a top psychology program, and I echo this– I have read many research statements for short-listed candidates in my department, and I have never seen a research statement shorter than two pages, and typically they are three or four.

September 5, 2012 at 10:27 am

I crowd sourced the question on FB and most responses said they favor a one page version. I suppose this could be a field specific thing. The humanities are def. one page. It strikes me that social sciences and psych in particular might be tending toward longer. I really wouldn’t recommend more than two though.

September 17, 2013 at 8:58 am

I am writing my own R.S. and have asked for copies from colleagues in both psychology and the life sciences. In all cases, the R.S. has been at least 4 pages. So, it doesn’t seem specific to just the social sciences. Maybe it’s a difference in the prestige of the universities, with R-1 preferring lengthier research statements, while liberal arts universities prefer a smaller research statement. Most candidates at R-1s also have lengthier C.V.s which would imply a longer R.S. no?

September 17, 2013 at 9:48 pm

October 15, 2013 at 8:17 pm

I’d seen a lot of recommendations online for RSs to have a hard limit of either one or two pages. When I asked my own (Education) professors about it, they said that two pages sounded short and that they’d seen everything from one page to ten pages but recommended keeping it no longer than 3-4. Right now mine is 2.5 pages.

August 30, 2012 at 10:24 pm

Thanks for this really helpful post! A few quick quick follow up questions that I’m sure may benefit others who have similar concerns. 1. As we situate our dissertation research within our fields (paragraph 2/3) does this mean we have license to use field-specific vocabulary or theoretical language? (as opposed to the cover letter, where we’re writing in a much more accessible voice?) 2. Also, many of the items in the 2nd, 3rd, and 4th paragraphs you suggest would seem to overlap quite extensively with the cover letter, making it hard to properly differentiate what goes where. For schools that require this statement, should we just strip down our cover letter and include some of these details in our research statement? Or, is there something I’m missing? And finally, 3. A bit of a mega-question, but what is the *point* of a research statement? Why do some schools have them? Understanding the reasons some departments request it would be helpful, especially in differentiating from the cover letter. Sincerely, Grad-student-on-the-market

September 1, 2012 at 8:58 am

Never strip down the cover letter. That is the document that opens the door for the reading of the other docs such as TS and RS. The distinction of the RS is that it can be more field-specific and far more detailed than what you can provide in the single para devoted to the research in the job letter. You can also situate the research vis-a-vis scholarship in the field (carefully and within limits, remembering the rules that the work described is YOUR OWN, and never to devote precious real estate to what OTHER PEOPLE have or have not done).

You can also briefly sketch the chapters of the dissertation as long as you give no more than about one sentence per chapter. One of the most tedious pitfalls of the RS is the exhaustive chapter-by-chapter description of the diss.

And re #3: that’s a great question. What IS the point? Basically, if the cover letter and CV open the door to your candidacy for the very first cut in a search comm member’s mind (say, from 500 to 100), then the RS gives more detailed indication that are a hard-hitting scholar with a sophisticated research program and a body of dense scholarship that will yield the publications you need for tenure, and also answer the question more clearly as to your fit for the job and for the department.

August 31, 2012 at 9:32 am

Is the Research statement the same as the diss abstract? My field seems to consistently ask for diss abstract and all the examples I have seen are two pages, with page one being a discussion of the project, it’s contributions, etc. and the second being ch descriptions.

August 31, 2012 at 12:05 pm

No, the diss abs. is an abstract of the diss! Common in English.

November 2, 2012 at 11:26 am

thanks for making this distinction. is there a length limit on the diss abstract?

September 1, 2012 at 12:08 pm

I’m in a STEM field and would disagree with limiting the RS to 1 page. Most research statements that I have seen (for searches at R1 schools) have been 2-3 pages. One aspect of this which may be different in STEM fields compared to social sciences/humanities is that in STEM you really should include between 1 and 3 figures in the research statement. We like data and we want to see yours. My research statements always included at least two figures – one from published work and one from a cool new result that wasn’t yet published (but was either in review or accepted but not in press, making it hard to scoop). Depending on the school I also sometimes included a picture of a cool method (it’s a pretty pic too) – that was typically done for SLAC apps where I was also making the point that I would be able to involve their students in that research. With figures that are actually readable, there is no way to get away with less than 2-3 pages for a research statement. Again I think this may be STEM specific but given how scientists read journals – most folks go straight to the figures and then later look at the text – this is probably a good tactic in those fields.

September 4, 2012 at 12:21 pm

I love the idea that a research statement could include figures. I’ve never seen one like this (I’m in biological anthropology) and have never thought this would be something that could be included.

September 5, 2012 at 10:25 am

In the hard sciences this is not uncommon.

September 1, 2012 at 4:33 pm

Forgive me for bringing up/asking the perhaps obvious. So no master’s thesis mention?

Also, you mention not providing two second projects. Would that still apply if one is far-away foreign, and the other local?

September 4, 2012 at 9:43 am

Another question on the MA – mine was empirical research published in a general science journal (Proc B) so I definitely need to mention it. But my question is whether I should explicitly say that this was my MA project?

I’m entering the job market ABD.

September 5, 2012 at 10:26 am

avoid framing yourself as a student, particularly MA.

September 4, 2012 at 9:32 am

I’d say, especially for humanities fields, the “baseline” of 1 page single-spaced that Karen mentions is correct. As she says in the post, there are obvious exceptions (STEM might want more, specific jobs might want more), but assuming 1 page without any other specific information is a good standard rule. In fact, from my own experience, 1 page generally works for any document that isn’t your vitae or your job letter.

The reason I say this is because you basically want to make a good impression pretty quickly. Job committees have limited time, and they are probably going to scan your document before deciding whether it is worth reading it in full. I’d also suggest reading up on document design, and making your documents easy to scan by putting in effective headers that give a powerful overall impression of your candidacy. You should also design those headers to lure your readers to look at your work more closely.

September 4, 2012 at 12:04 pm

I’m going through the process right now as an ABD, following advice from many quarters including TPII and a number of junior and senior faculty in top departments in my field. I have collected sample statements from 5 successful candidates and they are all in the 3-5 page range, closer to what the sociologist above describes. I have not seen a single statement at one page.

September 4, 2012 at 6:23 pm

When proposing future research, do you still recommend we avoid stating what others have NOT done? Can these types of statements, “yet others have not yet address xxx and yyy”, be helpful in justifying the need for our proposed topic?

It is always good to indicate, rather briskly, “in contrast to other work that has emphasized xxx…” or “no studies to date have examined xxxx.” What I am cautioning against is the very common temptation among young candidates to harp on and on about other scholars’ shortcomings, or how their diss topic is “badly understudied” (a phrase I’d give my right hand never to have to read again). Can the self-righteousness and just describe your work and its contribution.

September 7, 2012 at 12:54 pm

thanks for the post!

I had a question about not giving the sense that one is “extending” past work. As you say in this post: “Avoid the temptation to describe how you will “continue” or “extend” your previous research topics or approaches.”

In my case, my book will be comprised of about half new material and half dissertation research. “Extending” feels like an accurate word to describe the relationship between the diss and the book. Like, ‘Extending my diss research on xxx, the book offers new ways of thinking about issues yyy and zzz. …’

So is this the wrong way to describe the relationship between book and diss (even if it seems accurate?) What are *good* ways to talk about the relationship between the two when the book really does “build on” groundwork laid in the diss?

September 7, 2012 at 2:45 pm

This question actually requires a blog post on its own. There is a weird fixation among job seekers on the word ‘extend.” I don’t get it, and find it mystifying and irritating. Of course books or second projects will typically have some organic connection to the diss. But the insistence on saying that they “extend” the diss makes the DISS primary, and the new work secondary. But on the job market and in your career, the diss must NOT be primary. The diss is something a grad student writes. You are not applying to be a grad student. You are applying to be professor. So it’s the new material that should have primacy. Yet young job seekers are so myopically fixated on their diss that all they ever do is harp on and on about how every single damned thing they’re going to do next is basically a reworking of the diss material. Yuck! Who wants that?

As you can see, I am a bit reactive at this point…

September 7, 2012 at 2:53 pm

ok! I hear you saying that it is more about not giving the sense, throughout the letter, that the book is a mere “extension” of the dissertation, and that typically this word is overused by applicants and thus gives that impression. That makes sense. Personally, the sentence I noted above about is my only reference to the diss–the rest is all about the book and future project since I’m a postdoc and the diss is really in the past. 🙂 thanks!

September 15, 2012 at 7:19 pm

Thanks for the helpful guidelines, Karen!

How would you recommend shifting the focus of the paragraphs for those of us going on the market as postdocs? For me, I’ll have completed 2 years of a postdoc in Education, and so I have many new projects more relevant to my future research than my dissertation was. However, except for a few conference proceedings, I have no publications on my postdoc research yet. In fact, some of my proposed “new” research will be to continue what I began in my postdoctoc. Do hiring committees look down upon this?

Thanks for your advice!

September 22, 2012 at 5:58 am

Does anyone here know if this is an effective format for British Oxbridge postdocs as well? I’m finishing a UK PhD and pretty keen to stay in the country, and obviously these are madly competitive. I know my research is good, but the eternal question of how to make anything in the humanities sound important to other people, you know?

October 13, 2012 at 5:31 pm

Please tag this post so that it appears under the teaching and research statement category!

October 13, 2012 at 9:05 pm

October 29, 2012 at 4:38 pm

Karen: “Just never simply ASSUME that longer is better in an RS or in any job document”

Yours Truly: “Just never simply ASSUME that they are going to read what you write. Often they a long CV, RS, and list of publications to tick all the boxes and cover their backs.”

November 20, 2012 at 1:35 pm

If I consider teaching and curriculum development part of my research, is it okay to mention this in the RS–specifically if written for a university more focused on teaching than research? My assumption is that R1 schools would look down on this…?

November 20, 2012 at 2:56 pm

Unless you’re in the field of education, you can’t include teaching or curric. in a RS.

December 16, 2012 at 11:44 pm

Than you very much Karen. A valuable guide

December 31, 2012 at 7:37 pm

Does the rule of no more than one future project description apply to the field of developmental psychology?

*Please delete above post with my full name, I did not realize it would post

January 1, 2013 at 9:35 am

You would need to investigate that among your profs and colleagues. I don’t know the expectations of all fields well enough to advise.

September 18, 2013 at 4:10 pm

I wrote a research statement and asked a friend in my department look at it. She said I should include a paragraph on collaborative work I’ve done as well. The problem is that all of my “collaborative” work is really “assistance”. I do not want to frame myself as a graduate student, but I also see the value in highlighting my ability to produce scholarship with other people. Any thoughts on this, Karen or others?

September 27, 2013 at 8:37 pm

Many thanks! I searched through a tone of sites for samples and examples, but yours is the most helpful.

September 29, 2013 at 7:32 am

Does one use references and include a reference list in a research statement?

October 24, 2013 at 10:40 am

I’d like to know the answer to this question, too.

Karen’s advise (Do not refer to other faculty or scholars in the document. The work is your own. If you co-authored a piece, do not use the name of the co-author. Simply write, “I have a co-authored essay in the Journal of XXX.”) sounds like you shouldn’t, but I personally see more advantages (that’s what scholars are used to, you can reference one paper multiple times without much space, you give the full information of your papers) then disadvantages (mention other authors).

So some remarks on using reference lists/bibliographies would be really interesting.

October 11, 2013 at 2:17 pm

You mention that P4 should include: “A summary of the next research project, providing a topic, methods, a theoretical orientation, and brief statement of contribution to your field or fields.”

How specific do you need to get with that information? I want the review committees to see that I have good, viable ideas for future research, but at the same time I’m worried that by giving too many details my ideas are liable to get stolen…not to mention that more detail means a lot more space on the document and I’m already finding it really hard to keep it to 2 pages even just using pretty general info. All the example research statements from my field that I’m reading make generalized statements like, “This area of my research will focus on developing and characterizing the structure of smart multifunctional materials for infrastructure applications,” but that just doesn’t seem like enough…

Thanks for the advice! Your blog has been so valuable as I am preparing my application package. 🙂

October 24, 2013 at 8:52 am

Hi Karen, I am applying for a few Phd positions & programs around the world, and some programs ask for a research statement, some for a statement of purpose. I fell Ill during my master’s studies and it had impacted my studies to the point of taking a leave of absence(and is known by my referees). As I understand, I can mention that in a SOP, but not in a research statement. Is there anyway I can communicate to the admissions committee about my situation (within the scope of my application) ?

October 30, 2013 at 7:13 am

Hello, Karen, I am an old follower returning. In a research statement, do you give considerably less space to what is already published, books and articles, and much more space and detail to describe projects(s) in progress or about to be launched as research proposal applications?

October 31, 2013 at 7:32 am

I recommend balancing about half and half; in the case of very young/junior candidates, though, the previous/current stuff is going to far outweigh the future stuff.

November 6, 2013 at 12:32 am

I am applying to an R1 and part of the app package asks for a “statement of research interests”. it sounds self-evident, but this is different from a research statement, right? They are, in fact, wanting to know what my future research projects are, to ascertain if i am a good prospect, correct?

Many thanks, Karen and co.!!!

November 8, 2013 at 10:40 am

No. it’s the same thing.

November 8, 2013 at 2:35 pm

Hi, I am applying to graduate school, and some programs ask for a research statement. I have not done any independent research, but have worked in a lab under a postdoc for three years. As a undergrad, is it okay to refer to the postdoc by name and say that I was assisting? Should this be structured any differently than the model you gave above? Thanks!

January 20, 2014 at 5:02 am

I’m applying for a PhD scholarship and I’m required to write a research statement. Is there any different format for a PhD student to be or just follow the same as per above?

Thanks a lot!

February 7, 2014 at 10:58 am

Hi, Could you please let me know if it is proper to mention some of projects in a certain master course that one took? I asked this because I am applying for a position that almost there is not a direct relation between my master thesis and my prospective PhD supervisor’s research interests. Thank you in advance.

February 21, 2014 at 11:23 pm

If some of your research background was for a government agency and your results went to government documents and forms, are you allowed to include it in your research statement. For example, I am applying for a job that calls for a research statement in which I would be designing stream sampling plans and in the past I worked for state government designing and implementing SOPs for stream sampling and EPA reports. This experience is much more applicable to the job than my dissertation research is. In other words, is the RS more to show I can do research and think like a researcher or that I have done similar research in the past?

March 6, 2014 at 10:00 am

Hi, This post has been really helpful to me. I have a question about citations in a research statement. Should I cite relevant or seminal studies? Or is a research statement assumed to be written out of the authors own confidence, experience, and general knowledge of their field of study? If yes to citations, is there an optimal amount? Thank you!

April 26, 2014 at 11:01 am

I dont understand why I cannot name who I collaborated with, or worked with and claim complete ownership. Most of all disseration ideas comes out of a collaborative effort. Seems kinda lame to suddenly act like every idea is all mine without giving due credit.

April 26, 2014 at 12:00 pm

it’s not claiming ownership. It’s focusing on the work that YOU did as part of the project and not dispersing attention to other scholars, in this particular document.

April 28, 2014 at 10:09 am

I disagree. All of your recommendations are valid except for this one. In science and engineering, almost all dissertation work is collaborative; that’s how it works, either through industry applications, a reagent or mathematical technique, opportunity to apply theory to projects etc. Of course, the student has to compe up with the research questions and hypothesis and methodologies but it is very rare for one lab to have everything that the student needs in-house and even rarer for the work to be done in complete isolation (you don’t see that many two author papers in STEM fields these days). Including names of other people would actually be a good thing as it shows a willingness to interact and collaborate with a diverse set of people, picking up new skills and perspectives; this is how science is done these days. Of course the research thrust should be from the individual, but that is like a given.

October 26, 2014 at 8:00 pm

I am also in a STEM field, and all of my research has been collaborative to one degree or another. In my tenure-track applications last year, I mainly phrased my research statement to say that I work with YYY group on YYY, lead studies of ZZZ within the ZZZ Collaboration, and so on. I didn’t get any interviews.

This year I received some feedback from a new letter writer (and current collaborator), who thought that last year’s statement made it hard for outsiders to tell what specific ideas I had and what I specifically did about those ideas. When I rewrote my research statement to focus on those issues this year, I ended up with a stronger document that didn’t need to mention my collaborators at all — not because I tried to claim credit for everything, but because I wrote about my own contributions rather than the corporate identity.

Since jobs go to individuals and not corporations, I am strongly inclined to agree with Karen’s advice, even for STEM fields. In fact, it may be even more important for those of us with highly collaborative research to discuss our own contributions and leave our colleagues out of our research statements. The CV/publication list makes it clear that we interact and collaborate with others. The difficulty is to demonstrate what I actually did as author #13 (in alphabetical order) that makes me actually worth hiring.

April 29, 2014 at 5:03 am

Dear Karen, I am applying for a faculty position and have been asked to provide along with the usual CV and cover letter “Research Program Plan” and “Teaching philosophy”. Could you please or anyone inform me if the “Research Program Plan”is the same as the RS or a detailed research proposal? Additionally, should I include in the teaching philosophy an experience in my undergraduate that has shaped my teaching philosophy? Finally, should my TP include any courses ever taught or course proposals? Your candid response will be appreciated. Thanks

April 29, 2014 at 8:00 am

The RPP is the same as a RS. Please read all my posts on the Teaching Statement for more on that—do NOT include your undergrad experiences. Check out my column in Chronicle Vitae for more on that question–it’s the column on how to apply to a Small Liberal Arts College (SLAC) job.

July 16, 2014 at 3:39 am

Dear Karen, I am applying for a postdoc position in Spain and have been asked to provide along with CV and references, a “cover letter with a description of research accomplishments and statement of overall scientific goals and interests (approximately 1000 words)”. This messes up the usual structure I have in mind. What do you suggest? Two different files or a hybrid between them in one file? thanks

September 17, 2014 at 1:12 pm

Hi Dr. Karen,

I just wanted to say thanks for such an awesome article and the pointers.

Cheers Sajesh

October 13, 2014 at 4:15 pm

I am a bit confused about what a “statement of previous researc” looks like. Any insights?

October 14, 2014 at 12:59 pm

basically this RS doc, without anything about future research.

October 22, 2014 at 5:49 pm

I’m applying for a tenure track position in Strategic Management but my dissertation was on a topic related to my field, pharmaceuticals. How do I craft a RS if I really haven’t thought about future research in topics related to management but my teaching experience and work experience (line management) is directly related to management/leadership?

October 27, 2014 at 12:38 pm

Hi, Dr. Karen,

I’m applying for tenure-track positions in Computer Science. My current research focus (and for the last year and a half in my postdoc) has been in “data science”, primarily applied to biology; my dissertation work was in computational biology. I don’t want to focus on the biology aspect; I see this research being more broadly applicable. I also have significant industry experience from before my PhD; I spent 6 years doing work that was very relevant to this field of data science (in finance and in global trade), and I’d like to tie that industry work into my research statement. What do you think about this? Some have told me I should just talk about my postdoctoral research, while others have said the industry experience, since it’s very relevant, makes me a stronger candidate and I should tie it and my dissertation work into my postdoc and future research.

What are your thoughts? Thanks!

October 31, 2014 at 7:41 am

I am a young scholar in Communication. My research plan includes a description of past and current research projects (dissertation + 4 subsequent projects) and a description of short and long term projects (work in progress and three major research projects I want to undertake). I have been told this is not enough and I need more projects in my proposal. Only 2 pages for so many projects (including a detailed timeline) does not seem feasible.

November 3, 2014 at 7:50 pm

Dear Dr. Karen, First, let me thank you for your website. I’ve been reading it carefully the past few weeks, and I’ve found it very informative and helpful. I’m in something of a unique situation, so I’m not sure how to best make use of your advice on the RS, which seems aimed at newly minted PhDs. I have been in my current position, teaching at a community college, since 1997. During this time, I completed my doctorate (awarded in 2008). I taught abroad on a Fulbright scholarship in 2010-11, and during that time revised and expanded my dissertation for publication (this included contextual updates and one complete new chapter). I was fortunate enough to get a contract, and the book appeared in 2012; the paperback is coming out this month. Given my experiences, I want to make the move to a 4-year institution, if possible (I realize the odds are slim). A few of the ads I’m looking at are asking for a research statement. So, how do I best handle my circumstance in the RS? The dissertation and book are largely the same. Where should I provide the detailed description of my project and the chapter summaries (as you’ve recommended)? How can I avoid redundancies? Your advice is appreciated.

November 5, 2014 at 3:02 am

Dear Dr Karen,

I have read parts of your blog with great interest .. I need some advice.. if you have a research statement where one is combining two different streams of research, is this generally a good idea or would it be better to have a single stream? At the moment mine RS is nearly 4 pages (I have a short 3 page version of this).

Can you also give advice about an “academic plan” is this simply the 1-2 page “teaching statement”? Do yo have pointers/advice for this?

best regards,

November 9, 2014 at 10:50 am

Greetings Dr. Karen, hope this message finds you well.

I am applying for my first post-doc fresh out of my PhD. But I also did a Master’s prior to my PhD which resulted in publications and a thesis. That being said, do you think I should add my Master’s research to my research statement? I planned on putting it just above my PhD research. Thanks a lot 🙂

November 10, 2014 at 11:46 am

I’m wondering if it’s acceptable to mention personal qualities in an RS, such as being a collaborative worker or being able to acquire new skills rapidly (with concrete examples, that is). Normally I would put that in a cover letter, but it seems that cover letters are a thing of the past.

November 10, 2014 at 10:01 pm

No, that is not the place for that. Really, no part of the academic job application is the place for that.

November 19, 2014 at 6:47 am

Dear Karen, a special question… how do your rules above changing when writing a research statement for someone who has 4+years of AP experience and tons of research after dissertation?

Yours and other suggestions seem to be from the point of view of a grad/post-grad. Need some good insight/advise on how to to tailor a description of your research that spans many different threads and is perhaps quite a bit different from your dissertation.

November 26, 2014 at 9:51 pm

Dear Karen,

Thank you for this useful post. What about career goals? Does one mention those in the research statement or cover letter, if at all? For example, for NIH career development awards one has to write a one-page personal statement that includes career and research goals. The two are often aligned.

More specific, can /should one say things along the lines of: “My primary career goal is to become a successful independent investigator focused on xxx research.” or “I plan to secure a faculty position at a major university or research institute where I can engage in cutting edge research on xxx.”

Thank you for your insights.

Best regards,

November 27, 2014 at 9:19 am

This is more industry/business talk and not typical for academia. If you are articulating a complex research and teaching plan, it is UNDERSTOOD that you’re aiming for an academic career.

November 30, 2014 at 9:58 am

Dear Prof Karen Greeting, hope this greeting finds you well I have read this blog with great interest…In my opinion, writing teaching and research statements are very difficult than writing a PhD research… For your info that I have finished my PhD research with 17 publications in 2 years and 4 months and since that time (2 years)still writing my research statement and not finish yet..

November 30, 2014 at 10:13 pm

Thank you for your reply! Leaving this out will save me a lot of space. Best regards

January 14, 2015 at 11:17 am

I am applying for a grad program in engineering and the university requires me to write a research statement. I have no prior research experience nor have I thought about any topics for research. How do I approach this problem?

January 14, 2015 at 2:29 pm

I’m sorry, I don’t provide advice on applications to grad programs.

January 16, 2015 at 1:07 am

Okay, thank you.

January 23, 2015 at 11:33 pm

Hi, can I cite a reference in statement of research interests for a postdoctoral position? If so, do I include the reference of the citation at the bottom of the page? Also, do I title my statement of research interests page as ” statement of research interests”? Thank you.

February 4, 2015 at 10:18 am

I am applying for a 1 yr postdoc in the social science and humanities. The initial position is offered for one year with a possibility of renewal for up to one more year.

My plan is to use the postdoc opportunity to convert my dissertation into a book manuscript. I have a 2 yr plan which i believe is realistic. Roughly first yr review expand literature, reassess chapters, conduct addition interviews to build on insights. The second year would be analysis of data and writing and revising. How do I reduce this to a yr? Or do I propose it as a two yr endeavor?

February 5, 2015 at 9:39 am

to be blunt, you should skip the expanding of the literature, the reassessing, and the additional interviews. Things like this are what delay books. Transform your diss into a book mss with a one-year writing plan, and submit it for publication by the end of that year. Early in the year (or before you arrive) you send out proposals for advance contracts. This is what makes for a competitive postdoc app.

February 27, 2015 at 9:31 am

Thanks for your post. I am writing my RS with your comments as my reference. However, I have some concerns and wish you could offer some suggestions.

You mentioned that when writing RS, we should 1) Do not waste precious document real estate on what other scholars have NOT done. Never go negative. Stay entirely in the realm of what you did, not what others didn’t; and 2) Do not position yourself as “extending” or “adding to” or “building off of” or “continuing” or “applying” other work, either your own or others.

My doctoral thesis is to theoretically extend a theoretical model and empirically test it, which implies that the developer of the original model missed something to consider and I help do it. But if I take (1) and (2) into account. I may not be able to describe the rationale of my dissertation and further show the contribution.

In addition, (part of) my future directions is to increase the generalizability of the extended model, which means that I may apply it to my future research; and to discuss a potential issue in the extended model. However, if I take (2) into account, it seems that I cannot address it in the RS. Interesting enough, I found a number of model developers applied their developed theoretical models throughout the year with different research focuses and to validate the model. Should not such a way recommended to be addressed in the RS? Just a bit confused.

Would you please kindly help with the above? Thanks a lot.

March 4, 2015 at 2:16 pm

I am in public health and am a generalist so I have conduct research on a wide variety of topics. My masters thesis was on cesarean delivery guidelines and my dissertation is on the effect of legislation that bans certain breeds of dogs. I don’t want to pigeon hole myself into a specific topic area, but also don’t want to seem scattered. My research is all related, because it is on health systems or health policy, so I am trying to unify my RS with the theme of research that improves population health. Would you suggest that I list only my dissertation work and a future project that aligns with that, or should I also list my masters work and/or a separate project on a maternal and child theme?

March 11, 2015 at 6:19 pm

With regard to your recommendation to leave names of others out of the research statement, I am struggling with what to do for an edited volume with some *very* prominent contributors. I am the sole editor for the book, and I brought these contributors together. Should their names still be excluded from the research statement, or perhaps included elsewhere (perhaps in the cover letter or CV)?

Thank you for your very helpful postings.

March 12, 2015 at 7:20 pm

I find that many people overestimate the importance/prominence of the names and their value for any job doc. But if they include, like, Judith Butler and her ilk, then sure mention 1-2 such names in the RS.

July 7, 2015 at 12:51 pm

When applying for a faculty position (first job as assistant professor), would you recommend sharing the link of the applicant’s PhD dissertation thesis (if it is available online), if so where exactly?

Thank you very much for all the valuable information!

July 22, 2015 at 12:08 pm

Dear Karen –

I have a question for those out there encountering job openings for technical staff (like myself) with BS degrees requesting research statements. How do I write a RS based on this? Everything I’ve seen online has been geared towards RS for graduate programs or for those with newly minted PhDs.

August 14, 2015 at 6:19 pm

Dear Karen, Is there a difference between a “one page Research Plan” and a “Research Statement” ? Thank you for your generous advice through this blog.

August 29, 2015 at 8:39 pm

Thank you for the helpful posts. I am a postdoc applying for faculty positions, and they all ask something similar but different. It’s either a research statement, a statement of research interests, or a research plan. Do mean my previous research experience, what I plan to do, or both? A research statement sounds like a research summary, but I feel like I’m missing something. I appreciate any clarity you can bring on the subject.

September 2, 2015 at 9:22 am

Dear Dr. Karen, Some of the postdocs require to submit a C.V. and a list of publications. Does it mean that, for these particular applications, the C.V. should not include publications at all? Thanks!

September 2, 2015 at 9:49 pm

Sorry, just realized that had a wrong tab opened while typing the question.

September 24, 2015 at 10:01 pm

Hi Karen, This is a very helpful website indeed. I’ve been teaching university for 5 years (ever since finishing my PhD), and now am at a top 10 university (at least according to the QS rankings, if you put any stock in them). However, I’m applying for what I think is a better job for me at a research museum, one that would have me doing research and supervising grad students as well as doing outreach (something I’ve got piles of experience with). The application asks for a 2-page statement of scientific goals. I’m a little unclear as to how this differs from the research statement. Does it? If so, how? Thanks so much.

October 13, 2015 at 7:09 am

This was really helpful in writing a research statement. Thanks

November 11, 2015 at 1:17 pm

I see that some applications require a vision statement: “no longer than two pages, that outlines one or more major unsolved problems in their field and how they plan to address them.”. Any thoughts about the differences from a research statement?

January 14, 2016 at 7:28 am

How long should the research statement be if it has been requested as part of the cover letter?

May 20, 2016 at 8:24 am

Thank you very much for the very helpful advice, Karen!

I’m a final year PhD in psychology and applying for a postdoc now. The postdoc project seems very prescribed, to the extent that the announcement includes how many studies are planned to be conducted, what the broad hypotheses are and the broad theoretical background. Yet, the application involves an RS. What is the best way to frame a future research project here? Just tailor my diss to fit into the proposed postdoc topic?

July 1, 2016 at 3:10 pm

The place in this blog that should contain the 5-paragraph model doesn’t seem to be present. Instead I get a […]. Possibly a web configuration problem?

July 7, 2016 at 4:58 pm

Please read the para at the top of the post. This and a handful of other posts (about 5 in total) have been shortened so as not to overlap with the content of my book.

August 15, 2016 at 7:43 am

Thank you so much for your wonderful advice.

I have a question regarding the relationship between future research and the title of the position in question and how much overlap there should be between the two. Is it acceptable to propose research that is (this is history-based) from a slightly later/earlier period, or a slightly different geographical region than the position focuses on? Or is it better to align oneself entirely with the constraints of the position?

Many thanks!

August 23, 2016 at 9:46 am

I plan to limit my RS to two pages, but my career trajectory and publication record is a bit unusual. I’m a nationally regarded thirty-three year veteran high school teacher and recent postdoc (2013) from a top tier history department. I’ve been teaching alma mater’s most popular summer session course since 2014. It’s my mentor’s course, but he’ll be replaced with a tenured professor with an endowed chair upon retirement – as well he should. Cornell Press is “interested” in my diss, but…I’m currently revising the original proposal. I’ve also published as often in International Journal of Eating Disorders, Psychology of Women Quarterly and International of Alzheimer’s & Other Dementias as I have in The Journal of Urban History, Long Island Historical Journal and New York Irish History. I teach “the best and the brightest” at a socioeconomically and ethnically diverse public high school. I often publish with my adolescent students, so my scholarship is pretty eclectic. How, exactly, do I sell that to a hiring committee upon retirement from high school/transition to university teaching in June 2017?

September 12, 2016 at 6:29 pm

What is your take on using headings to organize the RS?

October 16, 2016 at 12:28 pm

I am up for tenure this year, and am applying for a tenured position at another school (mainly because I am trying to resolve a two-body problem). Given that I have been out of grad school for quite a while, have a book and many papers published, another book in progress, etc, should my tenure statement be longer than 1-2 pages? What would be a typical length for a mid-career statement?

October 17, 2016 at 1:14 pm

You can go onto a third page, if you’re on a second book.

October 19, 2016 at 4:08 pm

Hi Karen, I’m applying for tenure track jobs in English, and some applications ask for a research statement instead of a dissertation abstract, which is the more common of the two. I’ve been told that even if a dissertation abstract isn’t asked for, I should send one in with my application materials. If I’m asked for a research statement, do I still have to send a dissertation abstract as well? I’m a little worried about some overlap between the two (the obvious repetitions in contribution to the field, etc).

October 29, 2016 at 8:09 pm

I am being asked for a Scholarly Philosophy. Is this the same as a research statement? Are their any nuances of difference that I ought to attend to?

November 2, 2016 at 11:40 am

I’ve actuallynever heard that term. But I’d say it’s about the same as an RS, but perhaps with a bit more focus on wider contribution to the field.

November 8, 2016 at 10:55 am

Hello Karen,

I am a biologist on the market for a TT position (for more years than I would like to admit). I have always wondered whether including 1-2 figures or diagrams that help to illustrate your research plan would be helpful, and maybe even appreciated. I would like to know what you think.

We all know how overburdened search committees are. Pictures might help. Scientists are used to seeing such images in evaluating fellowship applications or grant proposals, why not research statements? I would think it would be a welcome change. So the potential benefit is you stand out and are more memorable, but you may also run the risk of alienating or offending someone, especially because this is uncommon.

Thanks for your posts and your book. I enjoy reading them.

November 10, 2016 at 9:53 am

Yes, in the sciences, diagrams are acceptable. It’s why science RSs are often 3-4 pages long. NOT in your cover letter of course.

January 12, 2017 at 11:56 am

Is it appropriate to put a date at the top or bottom of your statements?

August 4, 2017 at 5:32 am

I have been working as a fellow at a SLAC in the sciences and am directing undergraduate research that does not completely fit the mold of my usual work. Is it acceptable to mention these projects in the RS? Should I only mention ones that we will be trying to publish? Thanks

September 16, 2017 at 3:16 pm

Found some adjuncting this year after basically taking a year off last year. During that time, I was still working on getting material published from graduate school. This includes an article based on my dissertation. That articles is currently going through a revise and resubmit. The revise involves reframing and changing the names of important hypotheses. Do I discuss the work in my RS as it was discussed in my dissertation or talk about it as presented in this article yet to be expected for publication?

September 16, 2017 at 3:17 pm

accepted not expected

September 29, 2017 at 3:43 am

The part about not presenting your work as being better than other peoples’ is hard because constantly in your thesis you are setting up arguments like that! This is why my findings are interesting – because they are better than what other people did/found previously. The old paradigm was limited/wrong, hence my contribution is new/better. That is part of the academic writing genre! But I can see it will come across as much more mature if you downplay that in an application letter.

October 7, 2017 at 12:00 pm

Thanks for this great blog and the book!

I’m applying for a two-year postdoc. They say they want a “research statement,” but I really think they mean a proposal. This is short term, non-TT. I feel like the advice you give about “timeline, timeline, timeline!” is what will make this work better for this application.

Said otherwise, there is no time for a second project in this postdoc (or maybe you beg to differ?) Therefore it seems odd to talk about it.

October 7, 2017 at 2:11 pm

correct, they want a research proposal. Please read the chapters about that in my book. There is time in a two year postdoc to begin to launch a second project.

January 12, 2018 at 1:08 pm

I am just starting my higher education career. I only have my dissertation as published work. How do you suggest I handle to writing of my research statement given those circumstances?

August 27, 2019 at 6:26 am

Hi, I am a fresh PhD about to apply for my first job. I’ve been asked to write a scholarly agenda and am struggling to find what should be included in this. Any help would be great. The position is at a liberal arts college for a tenure track position in the biology department. Thanks

August 27, 2019 at 9:56 am

That would be the RS, and this blog post is about that. Also, check my book out, it has a chapter on this as well, updated from this post. If you need personal help, contact us at [email protected] to get on the calendar for editing help.

September 17, 2019 at 9:22 pm

Thank you for your excellent blog and book. I’m applying for a TT job where they don’t ask for a cover letter, but for a combined statement on research & teaching max 3p. In this case, do I still skip the letterhead and formal address? And what structure/format would you suggest?

Thank you in advance!

September 18, 2019 at 5:00 pm

if it’s truly not meant to be a letter, then don’t make it a letter! Just send a two page Rs and a one page TS nicely integrated into a single doc, with your name at the top.

December 23, 2019 at 6:23 am

Dear Karen, thank you for your wonderful advice here and in the book.I wonder regarding the the 1st para of the research statement. I have seen that many start by stating “I am a historian of X. My work focuses on Y in order to Z …

Is this what you mean by “A brief paragraph sketching the overarching theme and topic of your research,situating it disciplinarily”? would love to see an example of a good 1st para…

December 23, 2019 at 11:12 am

Lili, I provide examples to clients, so if you’d like to work with me, do email at [email protected] !

January 13, 2020 at 4:39 pm

I am just graduating as an undergrad and looking for entry-level research. Should I put something short on my interests if I do not have research experience, or is this section better to be left blank?

October 12, 2020 at 10:49 pm

Any differences with corona? I have two small ongoing projects related to covid. Other than that, I only have my thesis. Would mentioning these two projects be ‘too much’? They are not similar to each other: one has a clear logical link to my thesis, while the other is a new avenue that I want to pursue. They are not big enough to be my second project, but they are my current research. Should I mention them both? One? None?

January 6, 2022 at 11:51 am

Thank you for such detailed information! I searched on your site today in attempt to answer the question “what is a scholarly agenda,” and was pointed to this posting, which doesn’t seem correct, but I at least wanted to ask the question. Is the scholarly agenda a typical piece of writing for tenure processes? I’m about to go up for my three year review in a humanities-based tenure track position, where I am asked for one, and although I’ve written a draft, the university has no template, and in truth, I really don’t understand the aim of the scholarly agenda beyond the general idea of ‘where I want to be as a scholar and professor in three years.’ I’m looking for a blow-by-blow / paragraph-by-paragraph idea of how to structure the piece. I can’t find examples beyond law schools, which isn’t so helpful. Do you have any recommendations?

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How to write a statement of research interest for postdoc positions that already have a defineed research direction

I'm currently applying for a postdoc position in a particular lab. The lab has several postdoc positions available at this time, those postdocs will work on different aspects of a larger research project.The application need to include statement of research interest, CV, references and recommendation letters in one document, and also clearly state which position (which aspect of the research) I apply for.

I feel I'm a good fit for two of the positions. However, I don't know how to write a statement of research interest that is suitable for both positions, although those two aspects of the research are connected. From all the examples I saw for research statement, future research is a big part of it. With the research direction and aspects are clearly defined for the positions, what should I write in the section of future research?

• research-statement

• Welcome to academia.SE. The question would be more readable with a paragraph break or two. You can edit it to add them. –  Tommi Commented Aug 31, 2019 at 6:26

One way is to write an SOP that is a bit more general then you would do otherwise, but not so general as to seem unserious. If you do it carefully, it can be an advantage. I think that an SOP too tailored to a particular position might not be taken seriously -- too good to be true. But don't go to the other extreme of suggesting that your interests are so broad that you don't/can't specialize as needed.

I wouldn't recommend this for positions that were widely different, but it might be good here, as you say they are related.

But, as you say, the direction of the lab is set and a post-doc isn't likely to change that. If your research interests are aligned, your "future research" ideas will probably fit as long as you don't overemphasize the specifics more than needed.

This is a Three Bears sort of problem. Too general. Too specific. No, just right.

• 1 The last line is the true answer... –  Solar Mike Commented Aug 30, 2019 at 18:47
• I agree. Don't be too detailed and specific with your research interests. Just focus on the skills and the specific issues relevant to the position. You can write two different SOPs even though it is with the same lab. One position may be more aligned with your future interest and you can elaborate on specific future plans, etc. For the less aligned postdoc, just focus on the generic skills and aspects of the post doc and how that fit into your overall skills development? –  Poidah Commented Aug 31, 2019 at 0:07

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MSK Research Highlights, June 25, 2024

Tuesday, June 25, 2024

New research from Memorial Sloan Kettering Cancer Center (MSK) helped develop a machine-learning tool to help find cancer cells that remain after surgery; led to Food and Drug Administration approval for CAR T cell therapy against mantle cell lymphoma; tested a liquid biopsy approach that shows promise in detecting lung cancer; found checkpoint inhibitors were effective against endometrial and ovarian cancers with DNA-repair deficiency; and shed new light on mTOR’s role in metabolic enzyme degradation.

Machine-learning tool helps find cancer that remains after surgery

Many people who initially receive surgical treatment for solid tumors eventually have their cancer come back. A big reason why is minimal residual disease (MRD): small numbers of cancer cells that stay in the body and eventually form new tumors. MSK has led many efforts to detect MRD in recent years, including focusing on blood tests called liquid biopsies that are able to pick up low levels of tumor DNA in the blood. This can indicate the presence of cancer that remains after treatment.

In a new study, a team of scientists led by MSK breast oncologist Adam Widman, MD , and Dan Landau, MD, PhD , of Weill Cornell Medicine analyzed  a new liquid biopsy tool named MRD-EDGE. The researchers showed that this technology, developed by Dr. Widman and Dr. Landau, was able to find MRD after surgery in several cancer types — including colorectal cancer , lung cancer , breast cancer , and melanoma . MRD-EDGE uses machine learning to detect cancer mutations called single nucleotide variants and copy number variants. And the approach is able to find traces of cancer at levels that are too low to be picked up by other liquid biopsy tests. The investigators will continue to study the technology, which they say could help to determine which patients are not likely to benefit from chemotherapy after surgery, so that it is given only to patients who need it. Read more in Nature Medicine .

CAR T therapy proves effective for mantle cell lymphoma

On May 30, the United States Food and Drug Administration (FDA) announced the approval of lisocabtagene maraleucel (Breyanzi®), a chimeric antigen receptor (CAR) T cell therapy for adults with relapsed or refractory mantle cell lymphoma who have received at least two lines of systemic therapy. Mantle cell lymphoma is a rare, aggressive form of non-Hodgkin lymphoma . The treatment targets a molecule on the surface of blood cancer cells called CD19. The approval was based on a study led by  hematologist oncologist M. Lia Palomba, MD and showed that of 88 patients who received the therapy, the objective response rate was 83% — with 72% having a complete response. The median duration of response was nearly 16 months, and progression-free survival was just over 15 months. Dr. Palomba also contributed to the FDA approval of lisocabtagene maraleucel for relapsed or refractory follicular lymphoma, which was announced on May 15. Read more in the Journal of Clinical Oncology .

Machine learning-enabled liquid biopsy test may help close the lung cancer screening gap

Low-dose computed tomography (CT) is an approved screening test for lung cancer in high-risk populations. Yet many people who are likely to benefit choose not to have these scans. Investigators are looking for other screening methods. They include liquid biopsies that test patients’ blood for minute fragments of tumor DNA. In a recent study, a multicenter team that included researchers from MSK looked at one such liquid biopsy test.

The primary objective of the study was to train and validate a blood test that can detect fragments of DNA linked to genome-wide changes associated with lung cancer.  Blood samples from people confirmed to have lung cancer were used to train the test, which then applied machine learning to predict the likelihood of cancer, based on DNA fragments found. 

The investigators concluded the test has the ability to identify who is most likely to benefit from low dose CT. They report that the sensitivity of the test is 80%, with a negative predictive value of 99.8%, meaning that a patient with a test result of “not elevated” has a 2 in 1,000 chance of actually having a lung cancer. By using this test, the study concludes that the chance of finding a lung cancer using a follow-up low-dose CT is increased by 5.5 times in individuals with an “elevated” versus “not elevated” result.

“We are excited by these promising results and hope that the deployment of this assay and others like it will save many millions of lives through the earlier detection of cancer,” says MSK physician-scientist Luke Pike, MD, DPhil , the paper’s senior author. Read more in Cancer Discovery .  

Checkpoint inhibitors effective against endometrial and ovarian cancers with DNA-repair deficiency

Immunotherapy drugs called checkpoint inhibitors can be effective against cancers with a genetic abnormality called mismatch repair (MMR) deficiency or microsatellite instability (MSI). This flaw leaves cells with an inability to repair mistakes in the DNA. MSK gynecologic medical oncologist Claire Friedman, MD, led a clinical trial testing the checkpoint inhibitor nivolumab (Opdivo®) in people with endometrial (uterine) or ovarian cancers that are either MMR-deficient or otherwise have a high number of genetic mutations.

Results from the phase 2 trial in 35 patients show that nivolumab is effective in these cancers, with 59% responding to the drug, meaning their tumors shrank or disappeared. Two years after treatment, 65% had not had their disease return or progress. In addition, researchers were able to identify genetic and molecular biomarkers — in both the tumor and the tumor microenvironment — that indicated how well a patient would respond to the treatment. Knowing these biomarkers could help guide patient selection for future trials. Read more in Nature Medicine .

Study sheds new light on mTOR’s role in metabolic enzyme degradation

Human cells have to orchestrate more than 20,000 proteins to maintain healthy growth and survival. As conditions change, cells adapt by making new proteins and breaking down existing proteins. One common stressor that cells experience is a change in the availability of nutrients. Mammalian target of rapamycin (mTOR) is a protein that senses these changes and, when nutrients are scarce, can trigger a process known as autophagy to recycle amino acids and make their components available for reuse. It has been unclear, however, how nutrient stress affects protein degradation beyond autophagy — which only accounts for a portion of protein turnover. 

A new study from the lab of chemical biologist Heeseon An, PhD , at the Sloan Kettering Institute, found that mTOR also controls the breakdown of certain key metabolic enzymes via the ubiquitin pathway. The stability of one enzyme in particular, called HMGCS1, is tightly regulated by the mTOR-Ubiquitin pathway. This controls the abundance of HMGCS1 in cells and affects cellular sterol metabolism and cell proliferation. The study found that when mTOR is inhibited, a protein complex called CTLH E3 ligase induces the degradation of HMGCS1, while this degradation is inhibited when mTOR signaling is active. Overall, the study adds a new understanding of how mTOR regulates cellular metabolism: controlling the stability of key metabolic enzymes via the ubiquitin system. Read more in Molecular Cell .